Optimization of Adjuvant Radiation in Breast Conservation Therapy: Can We Minimize without Compromise?
نویسندگان
چکیده
منابع مشابه
Optimization of Adjuvant Radiation in Breast Conservation Therapy: Can We Minimize without Compromise?
Adjuvant breast radiation therapy after breast conservation surgery is recommended as it yields significant reduction in the risk of local recurrence, and confers a potential overall survival benefit. Although the standard breast radiation regimen has historically been delivered over 5-7 weeks; more novel, shorter courses of breast radiation are currently being employed, offering the advantage ...
متن کاملAdjuvant Systemic Therapy in Older Breast Cancer Women: Can We Optimize the Level of Care?
Defining optimal adjuvant treatment for older women with breast cancer is challenged by the lack of level-1 clinical evidence and the heterogeneity of the older population. Nevertheless, recommendations based on reviews of available evidence mainly from retrospective subgroup analyses and extrapolation of study results from younger patients, and expert opinions, may be useful to guide treatment...
متن کاملOptimization of tangential fields arrangement in the breast cancer 3D conformal radiation therapy
Introduction: The incidence of breast cancer increases with the rate of 1-2% at the world. Radiation therapy is one of the available choices for breast cancer treatment. The single isocentre half-beam block technique is considered as a standard technique to avoid hot and cold spots within the PTV. The major advantage of half beam technique is that the both contralateral breast...
متن کاملCan We Cure Breast Cancer with Adjuvant Trastuzumab?
The news of the results from 3 recent trials of adjuvant trastuzumab treatment in early breast cancer, showing a large reduction in cancer recurrence in women with HER2-positive (HER2+) disease, is a major success for the concept of targeted therapy using biological agents. Because 20% to 30% of all newly diagnosed women have HER2+ breast cancer, making trastuzumab available to all those who st...
متن کاملHow can we overcome tumor hypoxia in radiation therapy?
Local recurrence and distant metastasis frequently occur after radiation therapy for cancer and can be fatal. Evidence obtained from radiochemical and radiobiological studies has revealed these problems to be caused, at least in part, by a tumor-specific microenvironment, hypoxia. Moreover, a transcription factor, hypoxia-inducible factor 1 (HIF-1), was identified as pivotal to hypoxia-mediated...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Breast Cancer
سال: 2011
ISSN: 2090-3189
DOI: 10.4061/2011/321304